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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96-h LC50 is >213mg/L in zebrafish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
213 mg/L

Additional information

The acute toxicity of the test substance to fish was determined in a GLP-compliant test according to the OECD Guideline 203 (CG, 1994).

In this study, Zebrafish (D. rerio; 10 per concentration) were exposed to nominal concentrations of 0, 56, 100, 178 and 316 mg /L for 96 hours under static conditions. Test substance recovery was in the range of 95-105% of nominal values. The reported results are related to the average analytical concentrations of the test article measured at the beginning, at 48 hours and at the end of the test.

In the blank and in the test concentrations up to 101 mg/L no mortalities and abnormal behavior of the test fish was observed after the 96-hour exposure period. At a concentration of 181 mg/L two exposed fish died within 48 hours and at the highest test concentration of 315 mg/L all exposed fish died within 24 hours. Based on these results the 96-hour LC50 value was calculated to be 213 mg/L after 96 hours.