Registration Dossier
Registration Dossier
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EC number: 202-936-7 | CAS number: 101-37-1
Neurotoxicity
Administrative data
- Endpoint:
- neurotoxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP report without accordance to any guideline.
Data source
Reference
- Reference Type:
- publication
- Title:
- Anticonvulsant drugs. V. Some cyanurates.
- Author:
- Spielman, M.A.; Close, W.J.; Wilk, I.J.
- Year:
- 1 951
- Bibliographic source:
- J. Am. Chem. Soc., 73 (4), pp 1775–1777
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,4,6-triallyloxy-1,3,5-triazine
- EC Number:
- 202-936-7
- EC Name:
- 2,4,6-triallyloxy-1,3,5-triazine
- Cas Number:
- 101-37-1
- Molecular formula:
- C12H15N3O3
- IUPAC Name:
- tris(prop-2-en-1-yloxy)-1,3,5-triazine
Constituent 1
Test animals
- Species:
- mouse
- Details on test animals or test system and environmental conditions:
- No data
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Any other information on results incl. tables
The test substance showed complete anticonvulsant protection in mice (provoked by electroshock or metrazol) but with some alterations in normal behaviour such as ataxia or depression.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
