Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-820-9 | CAS number: 7757-82-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Sodium sulfate is not toxic to D. magna, the lowest LC50 found in a water hardness of 25 mg CaCO3/l and Ca:Mg ratio of 0.7 is 1766 mg/l. Under standard test conditions sodium sulfate is even less toxic, LC50 found there is 4736 mg/l. .
The test was found to be valid with restrictions because the study was well conducted with standard guidelines and chemical analysis. No GLP no analytical certificates and no raw data were documented. It is not known whether nominal or measured concentrations were used for the results. Sodium sulfate is stable in water over a period of 48h, therefore it is considered not to have an impact on the outcome and the conclusions of the test.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 766 mg/L
Additional information
Many publications are available on short-term toxicity of sodium sulfate to invertebrates, but most were not found reliable.
Four publications which describe six short-term tests were found reliable with restrictions. Mount (1997) performed two tests, one with Daphnia magna and one with Ceriodaphnia dubia. Soucek and Kennedy (2005) described two tests, one with Ceriodaphnia dubia and one with Sphaerium simile. Soucek (2007) performed a test with Ceriodaphnia dubia. Davies and Hall (2007) performed tests with Daphnia magna. None of these tests were performed under GLP, but they were all according to EPA guidelines with chemical analyses. Davies and Hall performed tests at several water hardness levels and 3 Ca:Mg ratios. The toxicity of sodium sulfate decreased with increasing water hardness. At a water hardness of 25 mg CaCO3/l and a Ca:Mg ratio of 0.7 the LC50 was 1766 mg/l. Under standard conditions the LC50 was 4736 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
