Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 201-297-1 | CAS number: 80-62-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption, other
- Remarks:
- calculation
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: EPI Suite calculation V4.11
- Principles of method if other than guideline:
- Calculation using EPISuite v.4.11 KOCWIN v2.00
Soil Adsorption Coefficient Program - GLP compliance:
- no
- Type of method:
- other: KOCWIN (Soil Adsorption Coefficient Program)
- Media:
- soil
- Specific details on test material used for the study:
- SMILES Structure: O=C(OC)C(=C)C
- Key result
- Type:
- Koc
- Value:
- 9.14 L/kg
- Remarks on result:
- other: MCI method
- Key result
- Type:
- log Koc
- Value:
- 0.961 dimensionless
- Remarks on result:
- other: MCI method
- Conclusions:
- Adsorption of MMA was calculated with KOCWin v. 2.0
Koc: 9.14 L/kg (MCI method)
log Koc: 0.961 (MCI method)
Adsorption to solid soil phase is not expected
Reference
Description of key information
Koc: 9.14 L/kg
log Koc: 0.961
Adsorption to solid soil phase is not expected.
Key value for chemical safety assessment
- Koc at 20 °C:
- 9.14
Additional information
Supporting information is vaialable in an adsorption/desorption study with radiolabelled methyl methacrylate:
Adsorption of MMA to soil was investigated using 5 different types of soil: sandy loam (=aquatic sediment), loamy sand, two types of loam, clay loam. pH varied from 5.2 to 7.5. Concentrations of test material (methyl methacrylate carboxy 14C) were: 0.5, 0.89, 1.6, 2.8, 5, 8.9 µg/mL. Concentration and assurance of integrity of the test substance throughout the study were confirmed by HPLC analysis. The adsorption phase (24 hours at 23 °C) was followed by 3 desorption phases. Distribution of MMA between aqueous and solid phases was followed by monitoring 14C-levels.
On the basis of its vapour pressure and its low adsorption to soil adsorption constants (Koc) ranged from 8.7 to 72 with an average value of 34 it can be expected that MMA volatizes rapidly from soil. Once adsorbed, MMA was less readily desorbed from soil. Desorption constants ranged from 14.8 to 263 with an average value of 95.
While methyl methacrylate must be classed as being quite mobile under laboratory conditions, care must be taken in predicting and interpreting its actual behavior under field conditions. In an outdoor environment,
other factors such as soil microbial degradation may significantly alter the actual field results from what would be predicted based solely upon the laboratory adsorption / desorption study. Additionally, as no correlation
was noted between the soil organic content and individual Koc values, care must also be exercised in predicting a detailed leaching behavior of methyl methacrylate in other, non-studied soils, based solely
upon an average Koc value obtained in the current study.
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