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EC number: 201-297-1 | CAS number: 80-62-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Principles of method if other than guideline:
- other (measured): equilibration: shake flask; analytical method: GC
- GLP compliance:
- not specified
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Supplier: Tokyo Kasei Co. (Tokyo)
- Analytical method:
- gas chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.38
- Temp.:
- 20 °C
- pH:
- ca. 7
- Remarks on result:
- other: The test originally was performed at room temperature and without a pH-value mentioned. Therefor we assumed a temperature of 20 °C. The test substance has no effect on the pH-value therefor it is assumed to be ca. pH: 7.0.
- Conclusions:
- Using a valid scientific method the partition coefficient of the substance was 1.38 at 20C.
- Executive summary:
Using a valid scientific method the partition coefficient of the substance was 1.38 at 20C.
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Methyl methacrylate from Ineos Acrylics, Batch No. Acrylics 98/15, purity: > 99 %
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 1.32
- Temp.:
- 20 °C
- pH:
- ca. 7
- Conclusions:
- Log Pow of methyl methacrylate was tested with the shake flask method equivalent to OECD 107. Log Pow was determined with 1.32.
Referenceopen allclose all
Study was performed without adjustment of pH value.
Description of key information
Two experimental studies for the determination of octanol-water partition coefficient are available according shake flask method with with nearly similar results: Log Kow 1.38 and log Kow 1.32. The highest value is used as key value.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.38
- at the temperature of:
- 20 °C
Additional information
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