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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Endpoint summary

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Administrative data

Link to relevant study record(s)

Description of key information

Niobium is not bioavailable via either route of exposure. It is not absorbed, not distributed within the body and excreted in faeces without prior absorbance.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

Absorption: Niobium is extremely inert and can only be dissolved under strongly oxidising conditions. Under physiological conditions, Nb metal cannot be absorbed via skin or gastrointestinal tract.

Distribution: After oral administration, Nb metal will remain in the GI tract until it is eventually excreted via faeces.

Metabolism As an inorganic substance without any bioavailability, Nb cannot be metabolised.

Excretion: Nb will not be absorbed via the oral route and ingested Nb will be eliminated via faeces without prior absorption.