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EC number: 270-737-2 | CAS number: 68477-54-3 A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
Mono-Aromatic (MoAr) 7 2.49
8 4.24
9 66.33
10 5.12
Naphthenic Mono-Aromatic (NMAr) 9 19.58
Total 97.76
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 90 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 17.2 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 90 and 17.2 mg/lg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 90 and 17.2 mg/kg soil dw, respectively. The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
Mono-Aromatic (MoAr) 6 0.44
7 2.99
8 5.10
9 83.11
10 0.95
Naphthenic Mono-Aromatic (NMAr) 9 2.40
Di-Aromatic (DiAr) 10 1.13
n-Olefin 10 0.54
n-Paraffin (n-P) 10 0.14
11 0.33
Total 97.12
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 89.6 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 17.2 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 89.6 and 17.2 mg/kg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 89.6 and 17.2 mg/kg soil dw, respectively. The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
Mono-Aromatic (MoAr) 7 1.55
8 31.91
9 17.86
10 2.89
12 2.29
13 0.67
Di-Aromatic (DiAr) 10 1.03
13 0.28
14 0.24
15 0.28
n-Olefin 5 0.27
10 21.06
11 0.41
i-Olefin 9 0.30
Total 81.03
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 103 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 19.7 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 103 and 19.7 mg/kg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 103 and 19.7 mg/kg soil dw for short-term (LL50) and long-term effects (EL10), respectively.The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
Mono-Aromatic (MoAr) 6 0.57
7 0.19
9 0.50
12 0.98
13 0.31
Di-Aromatic (DiAr) 10 0.27
n-Olefin 5 0.63
10 62.38
11 23.68
Total 89.52
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 290 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 55.6 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 290 and 55.6 mg/kg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 290 and 55.6 mg/kg soil dw, respectively. The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
Mono-Aromatic (MoAr) 7 0.75
8 35.64
9 17.80
10 2.99
12 0.35
13 0.23
Di-Aromatic (DiAr) 10 0.22
n-Cyclohexane (n-CC6) 7 0.11
iso-Naphthenic (i-N) 8 0.10
n-Olefin 5 0.58
6 0.17
9 0.61
10 23.76
i-Olefin 6 0.21
n-Paraffin (n-P) 7 0.12
8 0.18
9 0.30
Total 84.13
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 103 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 19.8 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 103 and 19.8 mg/kg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 103 and 19.8 mg/kg soil dw, respectively. The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
n-olefin 5 0.57
9 1.24
10 76.50
11 14.84
12 1.21
Total 94.37
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 285 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 54.6 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 285 and 54.6 mg/kg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 285 and 54.6 mg/kg soil dw for short-term (LL50) and long-term effects (EL10), respectively. The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- See Attached Justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- - Software tool(s) used including version:
See Field 'Attached justification'
- Model(s) used:
See Field 'Attached justification'
- Model description: See Field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- HC Block Type Carbon Number Concentration (%w/w)
Mono-Aromatic (MoAr) 8 1.51
9 42.57
10 7.04
Naphthenic Mono-Aromatic (NMAr) 9 0.98
10 0.36
Di-Aromatic (DiAr) 10 8.24
11 0.85
n-Olefin 5 0.22
9 0.13
10 26.65
11 4.67
Total 93.21
The constituents that could fit in more than one HC block, or that did not fit in any specific block, were placed in a relevant block that presented the highest toxicity. - Analytical monitoring:
- not required
- Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Study type:
- other: QSAR
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Remarks:
- Not required
- Duration:
- 28 d
- Dose descriptor:
- other: LL50
- Effect conc.:
- 111 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- mortality
- Remarks on result:
- other: QSAR prediction value
- Duration:
- 28 d
- Dose descriptor:
- other: EL10
- Effect conc.:
- 21.3 mg/kg soil dw
- Nominal / measured:
- estimated
- Conc. based on:
- other: QSAR prediction
- Basis for effect:
- reproduction
- Remarks on result:
- other: QSAR prediction value
- Validity criteria fulfilled:
- yes
- Conclusions:
- The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) for F. candida were 111 and 21.3 mg/kg dw respectively.
- Executive summary:
The QSAR predicted 28-d LL50 (mortality) and 28-d EL10 (reproduction) of the UVCB substance for F. candida were 111 and 21.3 mg/kg soil dw for short-term (LL50) and long-term effects (EL10), respectively. The model used for the calculations was the PETROTOX v4.0 model. PETROTOX is a well-documented and peer reviewed model that is widely used across the chemicals industry. This substance fits within the criteria of the model and there are no reservations about the validity of the model runs. It is expected that this data is reliable with restrictions.
Referenceopen allclose all
Description of key information
Key value for chemical safety assessment
Additional information
| Species | Substance CAS No. | LL50 / EL50 (mg/L) | EL10 (mg/L) |
| Folsomia candida | 68516-20-1 | 103 | 19.8 |
| Folsomia candida | 101316-62-5 | 90 | 17.2 |
| Folsomia candida | 68526-56-7 | 285 | 54.6 |
| Folsomia candida | 68477-54-3 | 103 | 19.7 |
| Folsomia candida | 94733-07-0 | 111 | 21.3 |
| Folsomia candida | 68478-10-4 | 290 | 55.6 |
| Folsomia candida | 65996-79-4 | 89.6 | 17.2 |
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