Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

From the acute and the prolonged toxicity studies, it is demonstrated that there is no acute toxicity issue. In the fish 21 day prolonged toxicity study (YKG32) the fish survived and grew, showing no evidence of toxicity at the highest measured concentration (0.94 mg/L)

There are three Daphnia reproduction studies available, YKG 45a, YKG 45b both conducted in 1994) and YKG 31b conducted in 1991. The oldest study suggests there is an effect on growth and reproduction and gives an NOEC of 0.012 mg/L, the data is analysed using Williams tests. The two later studies show no significant effects at the highest test level on survival growth or reproduction at 0.83 mg/l and 0.063 mg/L respectively these data were analysed using Dunnet’s test, a less sensitive statistical tool (all endpoints based on measured levels). From looking at the data there is a slight suggestion of effects however given the inert nature of the compound this is likely to be attributable to a physical effect due to the ingestion of particles (a similar size to algae) resulting in a dilution of food and therefore a slightly reduced growth and reproduction at the higher levels.