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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

ptBP affected the reproductive output of Daphnia magna with an estimated EC50 (21-d) value of 2.0 mg/L.  The NOEC and LOEC values were reported to be 0.73 and 2.3 mg/L (based on nominal concentrations), respectively.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.73 mg/L

Additional information

In a 21 -day reproduction study with Daphnia Magna, conducted in accordance with the OECD Guidelines for Testing of Chemicals No. 202, daphnids were exposed to ptBP at concentrations ranging from 0.073 to 7.3 mg/L, under semi-static conditions (EPA of Japan, 1995). The 21 d-EC50 value was determined to be 2.0 mg/L, based on nominal concentrations, while the NOEC and LOEC were 0.73 and 2.3 mg/L, respectively. A mixture of DMSO and HCO-40 was used as a solubilizer.