Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-679-0 | CAS number: 98-54-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
ptBP affected the reproductive output of Daphnia magna with an estimated EC50 (21-d) value of 2.0 mg/L. The NOEC and LOEC values were reported to be 0.73 and 2.3 mg/L (based on nominal concentrations), respectively.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.73 mg/L
Additional information
In a 21 -day reproduction study with Daphnia Magna, conducted in accordance with the OECD Guidelines for Testing of Chemicals No. 202, daphnids were exposed to ptBP at concentrations ranging from 0.073 to 7.3 mg/L, under semi-static conditions (EPA of Japan, 1995). The 21 d-EC50 value was determined to be 2.0 mg/L, based on nominal concentrations, while the NOEC and LOEC were 0.73 and 2.3 mg/L, respectively. A mixture of DMSO and HCO-40 was used as a solubilizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
