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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information


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Administrative data

Description of key information

Potassium diformate lacked potential for carcinogenicity in rodents (rats and mice). This can be extrapolated to formic acid and other formate salts including calcium diformate and supports the finding that calcium diformate is not genotoxic.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Dose descriptor:
2 000 mg/kg bw/day

Justification for classification or non-classification

No classification. Criteria of regulations 67/548/EC and 1272/2008/EC not met.

Additional information

Potassium diformate (up to 2000 mg/kg bw/day) did not show potential for carcinogenicity in two valid long-term rodent feed studies using rats and mice, respectively. This can be extrapolated to formic acid and other formate salts.

The tested formate dose compares to 2000 mg calcium diformate/kg bw/day.