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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
Toxicity of Autoxidized Squalene and Linoleic Acid,|and of Simpler peroxides, in Relation to Toxicity of Radiation
Author:
Horgan, V.J., Philpot, J. ST L., Porter, B.W. and Roodyn ,|D.B.
Year:
1957
Bibliographic source:
Biochem. J., 67, 551 ~ 558, 1957

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Dibenzoyl peroxide
EC Number:
202-327-6
EC Name:
Dibenzoyl peroxide
Cas Number:
94-36-0
Molecular formula:
C14H10O4
IUPAC Name:
diphenylperoxyanhydride
Details on test material:
Recrystallized benzoyl peroxide

Test animals

Species:
mouse
Strain:
other: R, CBA

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
213 mg/kg bw

Any other information on results incl. tables

20 umoles/mouse equivalent to 4.84 mg/mouse or 213 mg/kg bw

Applicant's summary and conclusion