Registration Dossier
Registration Dossier
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EC number: 204-589-7 | CAS number: 122-99-6
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC (21d) for 2-phenoxyethanol in a reproduction test with Daphnia magna was determined to be 9.43 mg/L (measured concentration) for reproduction and 49.2 mg/L (measured concentration) for weight and length. The LOEC (21d) regarding reproduction was 22.5 mg/L (measured concentration), the LOEC (21d) regarding weight and length was 110 mg/L (measured concentration).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 9.43 mg/L
Additional information
The chronic toxicity of 2-phenoxyethanol on
the reproduction of the water flea Daphnia magna STRAUS
was determined in a semi- static test according to OECD guideline 211
and U.S. EPA guideline OPPTS 850.1300 (BASF AG, 2006). Daphnids were
exposed to nominal concentrations (0, 10, 23, 50, 110 and 220 mg/L) of
2-phenoxyethanol (purity > 99.9% peak-area%) for 21 days, and
reproduction (young animals), swimming ability, length and weight of the
parent animals were measured.
In conclusion, the 21 day NOEC values for 2-phenoxyethanol in the
reproduction test were (nominal and measured concentrations) 10 mg/L for
reproduction (9.43 mg/L measured), 50 mg/L for weight and for length
(49.2 mg/L measured). The LOEC values were 23 mg/L for reproduction
(22.5 mg/L measured) and 110 mg/L for weight and length (nominal and
measured), the LC0values for swimming ability ofthe
adult animals were ≥ 220 mg/L (≥ 221 mg/L measured).
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