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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Link to relevant study record(s)

Description of key information

For HFC-134a and HFC-245fa, reliable experimental octanol-water partition coefficients are available, with LogKow values 1.06 and 1.35, respectively. Based on structural considerations, including the results from EPISuite and VCCLab estimations, it can be argued that the octanol-water partition coefficient of HFC 143a will be lower than the octanol-water partition coefficient of HFC-245fa, and comparable to that of HFC-134a.  Comparison of the experimental values for HFC-134a and HFC-245fa with the EPISuite and VCCLab estimations also confirms that available QSARs or models for these substances tend to over-predict the octanol-water partition coefficient.  As such, a value for Log Kow of 1.06 (being the experimentally determined Log Kow of HFC-134a) to be used for HFC 143a is justified.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information