Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1998
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
reliability scoring based on 2004 guideline.
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
0.3
Temp.:
40 °C
Remarks on result:
other: The pH was not reported.

Triplicate HPLC analyses yielded a mean log Pow of 0.3 ± 0.0.

Conclusions:
A log Kow value of 0.3 ± 0.0 at 40°C was determined for the substance using a relevant test method and in compliance with GLP. The result is considered to be reliable.

Description of key information

log Kow: 0.3 ± 0.0 at 40°C (OECD 117)

Key value for chemical safety assessment

Log Kow (Log Pow):
0.3
at the temperature of:
40 °C

Additional information

A measured log Kow value of 0.3 ± 0.0 at 40°C was determined for the registered substance using HPLC method in accordance with OECD Test Guideline 117 and in compliance with GLP. The result is considered to be reliable.