Registration Dossier
Registration Dossier
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EC number: 283-392-8 | CAS number: 84605-29-8
Endpoint summary
Administrative data
Description of key information
The test material is not acute toxic.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 3 100 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 2 300 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 002 mg/kg bw
Additional information
This substance does not show any evidence of toxicity via the oral route of exposure in animals when tested in accordance with OECD Guideline 401. The rat oral LD50 is 3,200 mg/kg in male and 3,100 mg/kg in female rats. Sublethal effects included hypokinesia and diarrhea; necropsy observations were unremarkable; no specific organ toxicity is evident; all animals showed expected bodyweight gain during the course of study.
This substance does not show adverse toxicity effects via the dermal route of exposure in animals when tested in accordance with OECD Guideline 402. The rat dermal LD50 is greater than 2002 mg/kg in male rabbits. Prostration in one animal, and desquamation of the skin noted on test day 11 were observed. No specific organ toxicity is evident.
This substance does not show evidence of systemic toxicity, or specific organ toxicity, via the inhalation route of exposure in animals when tested in accordance with OECD Guideline 403.
Justification for classification or non-classification
In accordance to Directive 67/548/EEC and EU CLP (Regulation (EC) No. 1272/2008), classification of this substance is not required for acute toxicity.
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