Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Read-across from analogue substances.
Aluminium-magnesium-zinc-carbonate-hydroxide (EC 423-570-6):
* First reliable study (OECD 201, according to GLP principles): A filtered solution prepared at a loading rate of 100 mg ALUMINIUM-MAGNESIUM-ZINC-CARBONATE-HYDROXIDE-HYDRATE per litre contained an average concentration of 0.15 mg test substance per litre when based on Aluminium and a test substance concentration of 0.12 mg per litre when based on Zinc. Algal cells exposed to this solution for 48 hours were not affected (NOEC - 0.12 mg test item/L based on Zn, 0.15 mg test item/L based on Al). Therefore, the EC50 for both growth rate reduction and yield could not be reached.
* Second reliable study: Under the conditions of the test (saltwater), Aluminium-magnesium-zinc-carbonate-hydroxide-(hydrate) did not significantly inhibit
cell growth or reduce growth rate of Skeletonema costatum at concentrations (loading rates) up to and including 180 mg/L (NOEC).
Alcamizer 5 (EC 422-150-1):
ErC50 Algae freshwater (OECD 201 and GLP guidelines, no Mg and Al detected): > 18 mg test item/L (> water solubility)
NOErC (72h) Algae fresh water: 10 mg test item/L (> water solubility)
Overall conclusion: ErC50 > 0.15 mg test item/L based on Al measured concnetrations (i.e. > solubility limit in water)

Key value for chemical safety assessment

Additional information

Based on reliable studies with Alcamizer 5 and Aluminium-magnesium-zinc-carbonate-hydroxide, both analogue substances,

[carbonato(2-)]hexadecahydroxybis(aluminium)hexamagnesium is considered to have an ErC50 > 0.15 mg test item/L based on Al measured concentrations (i.e. > WS; loading rate was 100 mg/L).