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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: oral

Currently viewing:

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: insufficient information to determine reliability

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Kagan G.Z.
Year:
1965
Bibliographic source:
Gig i Sanit, 30, 351, (1965) |cited in the MAK-Evaluation, Triethylamin (1983)

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Triethylamine
EC Number:
204-469-4
EC Name:
Triethylamine
Cas Number:
121-44-8
Molecular formula:
C6H15N
IUPAC Name:
triethylamine
Details on test material:
Triethylamine, no further data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Duration of treatment / exposure:
6 months
Frequency of treatment:
no data
Doses / concentrations
Remarks:
Doses / Concentrations:
0.1; 1; 10 mg/kg
Basis:

Control animals:
yes

Results and discussion

Results of examinations

Clinical signs:
effects observed, treatment-related
Mortality:
mortality observed, treatment-related
Details on results:
10 mg/kg: changes in reflexes
1 mg/kg: minimal changes in reflexes
0.1 mg/kg: no effect

Effect levels

Dose descriptor:
NOAEL
Effect level:
0.1 mg/kg bw (total dose)
Sex:
not specified

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion