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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Leopomis macrochirus.  96hr LC50 >10,000mg/l (protocol: no data)
Menidia sp.   96hr LC50 >10,000mg/l (protocol: no data)
Leuciscus melanotus.   48hr LC0 >10,000mg/l (protocol: no data)
Poecilia reticulata. 7 day LC50 229mmol/l (protocol. no data)
Oncorhynchus mykiss  96hr LC50 =16,000mg/l (protocol: no data)
Oncorhynchus mykiss  96hr LC50 >16,000mg/l (protocol: OECD 203)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
10 000 mg/L

Marine water fish

Marine water fish
Effect concentration:
10 000 mg/L

Additional information

A number of studies have been carried out using multiple species, both fresh and salt water. One study in two species is sufficiently well reported to judge it as reliable and this is used to derive the key parameters. All the other available experimental studies, whilst not individually robust, report data that is consistent with the key study and provide strong evidence that methoxyethanol is practically non-toxic to fish over the acute timeframe. The measured data is consistent with the QSA information that predicts an LC50 of 21.2g/l for freshwater fish and 36.7g/l for saltwater fish.