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Since the long-chain alkyl methacrylate esters (C12 – C22) are readily biodegradable an indirect exposure to soil via sewage sludge transfer is unlikely. In addition, direct releases to soil from point sources are not known and very unlikely due to the extremely low vapour pressure of the substances. Therefore, significant exposure of terrestrial compartments is not expected.

At production sites, the esters are handled in closed systems for polymerisation.

Diffuse releases into the environment from residual monomers in the polymeric products are not of concern due to the extremely low vapour pressure of the substances.

The esters are metabolised via cleavage of the ester bond, the resulting moieties are substrates for the fatty acid metabolism and for the valine pathway of the tricarboxylic acid cycle, respectively. These are pivotal metabolic pathways of all organisms, and therefore, biomagnification in the food chain and, in consequence, secondary poisoning are not expected.

In conclusion, based on such low exposure levels studies on terrestrial organisms are not required.