Registration Dossier

Diss Factsheets

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

LogKoc = 0.99 (KOCWIN, v2.0, MCI model)

LogKoc = 1.42 (KOCWIN, v2.0, LogKow model)

Key value for chemical safety assessment

Koc at 20 °C:

Additional information

Diethyl ether has a LogKow <3 (=1.05), is not an ionisable substance, and is not surface active. As a result, the substance meets the criteria for waiving as outlined in Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7a: Endpoint Specific Guidance, R.

As supporting information, a QSAR prediction was made for the Koc value, using KOCWIN. The MCI model was selected as the more reliable value, as it made the better prediction, in comparison with experimental data, for an analogue molecule. The QSAR result is considered to be credible and suitable for the purposes of risk assessment.