Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1982

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Di(benzothiazol-2-yl) disulphide
EC Number:
204-424-9
EC Name:
Di(benzothiazol-2-yl) disulphide
Cas Number:
120-78-5
Molecular formula:
C14H8N2S4
IUPAC Name:
di(benzothiazol-2-yl) disulphide
Details on test material:
SH-82-009, 2,2'-dithio-bis-benzothiazole

Method

Type of population:
general
Controls:
test substance 70% in petrolatum
Route of administration:
dermal

Results and discussion

Results of examinations:
0/53 volunteers with positive skin reactions

Any other information on results incl. tables

the test substance was negative in the Repeated Insult Patch Test (0/53 volunteers with positive skin reactions)

Applicant's summary and conclusion