Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-218-8 | CAS number: 5329-14-6
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: Data Assessment
- Adequacy of study:
- supporting study
- Study period:
- 2010
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
- Objective of study:
- toxicokinetics
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Sulphamidic acid
- EC Number:
- 226-218-8
- EC Name:
- Sulphamidic acid
- Cas Number:
- 5329-14-6
- Molecular formula:
- H3NO3S
- IUPAC Name:
- sulfamic acid
- Test material form:
- solid: crystalline
Constituent 1
- Radiolabelling:
- no
Results and discussion
Main ADME resultsopen allclose all
- Type:
- absorption
- Results:
- An at most low absorption in the gastrointestinal tract and through the skin is expected for sulphamidic acid
- Type:
- metabolism
- Results:
- Therefore no indication of the importance of the metabolism of the test item
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): low bioaccumulation potential based on study results
Given the very high water solubility and estimated low octanol/water partitioning coefficient, an at most low bioaccumulation is expected. Absorption via oral or dermal exposure is expected being low (both 10% assumed) and based on high particle size inhalation exposure is not relevant (10% absorption assumed as worst case).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
