Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 306-004-1 | CAS number: 95465-89-7
Endpoint summary
Administrative data
Description of key information
Members of the C4 low 1,3-butadiene category are flammable gases at room temperature and therefore the requirement for data on skin and eye irritation is waived in accordance with REACH Annexes VII and VIII (column 2 adaptation). All members of this category are gases, and liquid gases may cause burns and frostbite due to the extreme cold of the liquid.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
In accordance with REACH Annexes VII and VIII column 2 adaptation, studies on skin and eye irritation do not need to be conducted as members of the C4 low 1,3-butadiene category are flammable gases at room temperature
No skin or eye irritation studies have been conducted with streams in this category (CAS Numbers; 91052-98-1, 92045-23-3, 95465-89-7, 95465-90-0 and 95465-91-1) but based on physical chemical properties, the liquid gases may cause burns and frostbite due to the extreme cold of the liquid. There are no data available as no skin or eye irritation studies have been conducted with members of this category but category members are not expected to be irritating. There are no indications of irritation from repeat dose inhalation studies.
Effect level: empty Endpoint conclusion: Adverse
effect observed
Justification for classification or non-classification
Members of the C4 low 1,3-butadiene category are flammable gases at room temperature. There is no evidence to suggest that category members are irritating and therefore do not warrant classification under Dir 1999/45/EC or GHS/CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
