Registration Dossier
Registration Dossier
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EC number: 306-004-1 | CAS number: 95465-89-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Members of this category are gases at standard temperature and pressure, therefore conducting an aquatic ecotoxicity test is technically difficult and based on exposure estimates the test may not be relevant. Therefore, the use of a QSAR to predict the ecotoxicity of representative components of these streams is an appropriate technique for aquatic toxicity. In addition, it is difficult to assess the toxicity of UVCB streams using standard test methods. Instead, it is more appropriate to consider the toxicity of representative components of these streams. As such, as the category is made up of C4 hydrocarbons, representative hydrocarbon C4 substances butane (CAS no. 106-97-8), isobutane (CAS No. 75-28-5), isobutene (CAS No. 115 -11 -7) and butene (CAS No. 25167 -67 -3) have been used as read-across.
The use of ECOSAR is appropriate for this Category as these streams falls within the applicability domain of the model. The calculated 96 hour EC50 values for representative substances within this Category showed a short term toxicity to aquatic algae and cyanobacteria to be in the range 7.7 - 14.9 mg/L.These values have been used in the PBT assessment of this category.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 7.7 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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