Registration Dossier
Registration Dossier
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EC number: 220-767-7 | CAS number: 2893-78-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
ASRI test has been performed on both TCCA and CYA according to OECD guideline 209.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 51 mg/L
- EC10 or NOEC for microorganisms:
- 10 mg/L
Additional information
TCCA:
A study was performed to assess the effect of TCCA on the respiration of activated sewage sludge (Clarke 2002). Activated sewage sludge was exposed to an aqueous solution of the test material at concentrations of 1.0, 3.2, 10, 32 and 100 mg/L for a period of 3 hours at 21°C with the addition of a synthetic sewage as a respiratory substrate. The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and a reference material 3,5 -dichlorophenol. The effect of the test material on the respiration of activated sewage sludge gave a 3 hour EC50 of 51 mg/L. The NOEC after 3 hours exposure was 10 mg/L.
CYA:
A study was performed to assess the effect of the monosodium salt of cyanuric acid on the respiration of activated sewage sludge. (Clarke 2007). Activated sewage sludge was exposed to an aqueous solution of the test material at concentrations of 480, 850, 1500, 2700 and 4500 mg/L (equivalent to 363, 643, 1134, 2041 and 3402 mg cyanuric acid/L) for a period of 3 hours at a temperature of 21°C with the addition of a synthetic sewage as a respiratory substrate. The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and a reference material 3,5 -dichlorophenol. The effect of the test material on the respiration of activated sewage sludge gave a 3 hour EC50 of >4500 mg/L (equivalent to 3402 mg cyanuric acid/L). The NOEC after 3 hours exposure was 2700 mg/L (equivalent to 2041 mg cyanuric acid/L).
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