Registration Dossier
Registration Dossier
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EC number: 203-400-5 | CAS number: 106-46-7
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No OECD guideline or GLP study defined.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 989
Materials and methods
- Principles of method if other than guideline:
- Metghod: other
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- 1,4-dichlorobenzene
- EC Number:
- 203-400-5
- EC Name:
- 1,4-dichlorobenzene
- Cas Number:
- 106-46-7
- Molecular formula:
- C6H4Cl2
- IUPAC Name:
- 1,4-dichlorobenzene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Fischer 344
- Sex:
- male
Administration / exposure
- Route of administration:
- other: gavage
- Vehicle:
- other: corn oil
- Doses:
- 500 mg/kg
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Any other information on results incl. tables
see: executive summary
Applicant's summary and conclusion
- Executive summary:
After single oral administration of 770 mg/kg 1,4 -dichlorobenzene, an increase in the formation of hyaline droplets in the renal cortex was observed in male rats.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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