Registration Dossier
Registration Dossier
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EC number: 203-400-5 | CAS number: 106-46-7
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms
- Author:
- Call DJ, Brooke LT, Ahmad N, RIchter JE
- Year:
- 1 983
- Bibliographic source:
- EPA 600/3-83-095, US EPA, Duluth, MN: 120 p
Materials and methods
- Principles of method if other than guideline:
- Ten to 20 midge larvae in their 3rd or 4th instar stage of developement were exposed in 8.5 cm glass dishes filled to a depth of 2.6 cm (ca. 200 ml volume) with test solution. Each chamber with a 3 mm glass overflow tube contained lake water plus a small amount of food (ratio of 1 l : 0.0025 l), with a fine layer of sand on the bottom.
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,4-dichlorobenzene
- EC Number:
- 203-400-5
- EC Name:
- 1,4-dichlorobenzene
- Cas Number:
- 106-46-7
- Molecular formula:
- C6H4Cl2
- IUPAC Name:
- 1,4-dichlorobenzene
- Details on test material:
- purity 97%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- concentrations were analysed daily
Test organisms
- Test organisms (species):
- other: Tanytarsus dissimilis
- Details on test organisms:
- Tanytarsus dissimilis Johanson 1937
Study design
- Study type:
- laboratory study
- Test type:
- other: static or flow-through
- Water media type:
- freshwater
- Type of sediment:
- not specified
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 13 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 10.9-15.6
Any other information on results incl. tables
The author recommends organisms such as Tanytarsus dissimilis with consistently high tolerances to a broad range of chemical classes should receive minimal effort.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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