Registration Dossier
Registration Dossier
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EC number: 247-781-6 | CAS number: 26544-38-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of the substance to micro-organisms was evaluated in an activated sludge respiration inhibition test conducted in accordance with OECD Guideline 209.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 800 mg/L
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
In the key study entitled “Activated Sludge, Respiration Inhibition Screening Test on Test Substance OS-18230” (Kung, Ricerca, 1995) and based on OECD Guideline Method 209, activated sludge obtained from a domestic sewage treatment plant is used as the microbial source to test the toxicity of the substance. The effects of the test substance on micro-organisms was determined by measuring the microbial respiration rate under defined conditions in the presence of different concentrations of the test substance (1, 10, 100, 1,000 and 10,00 mg/L).The test substance was determined to be non-inhibitory to microbial respiration at concentrations lower than 100 ppm (NOEC estimated at 100 mg/L). However, the substance was shown to inhibit microbial respiration at higher concentrations with an estimated EC50of 800 ppm (mg/L).
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