Registration Dossier
Registration Dossier
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EC number: 247-781-6 | CAS number: 26544-38-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substance was not shown to be readily biodegradable; degradation of 9.9% at 28 d was reported in the key study.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The substance was not shown to be readily biodegradable in two guideline studies. The key study was a closed bottle test conducted according to OECD Guideline 301D, indicating 9.9% biodegradation after 28 days. The observed degradation rate of 9.9% is only slightly below the threshold of 10% degradation, which initiates the 10-day window; this result is suggestive that primary biodegradation is occurring, although at a level insufficient to show inherent biodegradability. One supporting study was a manometric respirometry test conducted according to OECD Guideline 301F, indicating 0% degradation in 28 days. In a second supporting study, a validated QSAR model (BIOWIN v4.10, in EPI Suite) predicted that the substance was not readily biodegradable, although ultimate biodegradation was predicted in the timeframe of weeks.
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