Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-236-9 | CAS number: 79-94-7
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
GLP/guideline compliant 28-d study in L. varigaetus (2% TOC)
GLP/guideline compliant 28-d study in L. varigaetus (5.0% TOC)
GLP/guideline compliant 28-d study in C. riparius
GLP compliant 14-d study in C. tentans
GLP compliant/28-d study in Hyalella azteca
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 90 mg/kg sediment dw
Additional information
The toxicity of TBBPA to sediment dwelling organisms was tested in 5 studies:
1) Breteler (1989): 14 d study in Chironmus tetans at nominal concentrations 13, 25, 50, 100, and 200 mg/kg TBBPA.
2)Krueger et al. (2005): 28 day study in Chironomous riparius at nominal concentrations 63, 125, 250, 500, and 1000 mg a.i./kg.
3) Krueger et al. (2002): 28 day study in Lumbriculus variegates in 2% total organic carbon (TOC) sediment at nominal concentrations of 90, 151, 254, 426, 715, 1200 mg/kg.
4) Krueger et al. (2001): 28 day study in L. varegates in 5% TOC sediment at nominal concentrations of 90, 151, 254, 426, 715, 1200 mg/kg.
5) Krueger et al. (2006): 28 day study in Hyalella azeteca at nominal concentrations of 63, 125, 250, 500, 1000 mg/kg TBBPA.
The four 28 day studies were conducted under GLP conditions and according to international guidelines with analytical confirmation of sediment concentrations.
The 28 day NOEC, expressed as mg TBBPA/kg sediment dry weight, ranged from 90 - 254. The lowest NOEC was observed in L. varigatus in the sediments that contained a TOC content of 2%, while the highest was in the same species tested in sediments with a 5% TOC content.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
