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Administrative data

Key value for chemical safety assessment

Additional information

Ethylenediamine, propoxylated was negative in three assays:

- bacterial reverse mutation assay

- in vitro HPRT cell mutation assay (OECD 476)

- in vitro micronucleus test (OECD 487)

In addition, the results for one further assay from Ethylenediamine, ethoxylated and propoxylated, was also negative.

- Negative result read across from an in-vitro chromosome aberration test with Chinese Hamster V79 cells

Short description of key information:
Three in vitro mutagenicity tests using different end points were all negative. Therefore further testing is not required.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The results from in-vitro testing of genetic toxicity do not warrant classification according to EU GHS.