Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
toxicity to terrestrial plants: long-term
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
toxicity to soil macroorganisms except arthropods: long-term
Type of information:
experimental study planned (based on read-across)
Study period:
After approval by ECHA
Justification for type of information:
The soil hazard category 3 (ECHA 2017, guidance part R7(c) Table R.7.11—2) has been derived for the substance based on the expected persistence of the silanol hydrolysis product, methylsilanetriol. In accordance with the screening assessment for soil hazard category 3 substances, a PNECsoil has been calculated from the aquatic data on the basis of the equilibrium partitioning method. The PNEC calculated by Equilibrium Partitioning has been derived for the purpose of chemical safety assessment and the risk characterisation ratios are below 1. In addition, a confirmatory long-term soil toxicity test should be conducted. A chronic earthworm reproduction test with methylsilanetriol is proposed to fulfil the testing requirements for soil hazard category 3.
Qualifier:
according to guideline
Guideline:
OECD Guideline 222 (Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei))

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Trimethoxy(methyl)silane
EC Number:
214-685-0
EC Name:
Trimethoxy(methyl)silane
Cas Number:
1185-55-3
Molecular formula:
C4H12O3Si
IUPAC Name:
trimethoxy(methyl)silane

Results and discussion

Applicant's summary and conclusion