Registration Dossier
Registration Dossier
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EC number: 202-716-0 | CAS number: 98-95-3
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Allergien gegenüber aromatischen Amino- und Nitroverbindungen.
- Author:
- Schulz, K.H.
- Year:
- 1 962
- Bibliographic source:
- Berufsdermatosen 10, 69-91
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- Epicutaneous test with patients suffering from dermatitis.
- GLP compliance:
- no
Test material
- Reference substance name:
- Nitrobenzene
- EC Number:
- 202-716-0
- EC Name:
- Nitrobenzene
- Cas Number:
- 98-95-3
- Molecular formula:
- C6H5NO2
- IUPAC Name:
- nitrobenzene
- Details on test material:
- - Name of test material (as cited in study report): nitrobenzene
- Analytical purity: no data
Constituent 1
Method
- Type of population:
- general
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Epicutaneous tests for the evaluation of nitrobenzene (applied concentration 1%) as a potential sensitizer in 3
persons were negative (no details specified).
3/15 persons, sensitized by p-phenyldiamine or azo-dyes showed a weak reaction to nitrobenzene.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
