Registration Dossier
Registration Dossier
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EC number: 203-539-1 | CAS number: 107-98-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A GLP-study according to ASTM method is available for propylene glycol methyl ether. This study is supported by a GLP-study equivalent to OECD guideline 201 and a non-GLP study according to DIN 38412.
Key value for chemical safety assessment
Additional information
In the key study, exposure concentrations ranged from 63 to 1,000 mg/l (nominal concentrations). A slight inhibition on cell count (7.1%) was observed after 7 days for all of the concentrations except for 500 mg/l. No significant inhibition was observed for biomass. Based on the nominal concentrations, the EC50 (biomass) was determined to be superior to 1,000 mg/l.
In the two supporting studies, concentrations ranging from 1 to 1,000 mg/l and from 31.25 to 500 mg/l were used. None of the concentrations tested caused more than 21% reduction in cell number compared to the mean cell number in the controls. Based on the nominal concentrations, the EC50 values were determined to be superior to 1,000 mg/l and 500 mg/l, respectively.
The 7 -day EC50 greater than 1000 mg/l will be taken into acount for the risk assessment.
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