Registration Dossier
Registration Dossier
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EC number: 700-442-0 | CAS number: 73573-88-3
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: Derek Nexus software
- Type of information:
- other: DEREK Nexus software
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: DEREK Nexus software
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- other: Derek Nexus software, version 2.0.2
- GLP compliance:
- no
Test material
- Reference substance name:
- (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate
- EC Number:
- 700-442-0
- Cas Number:
- 73573-88-3
- Molecular formula:
- C23H34O5
- IUPAC Name:
- (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate
Constituent 1
Results and discussion
In vivo
- Irritant / corrosive response data:
- Computational Toxicology Summary was prepared by DEREK Nexus version 2.0.2 software, and the result for ocular toxicity is negative.
Any other information on results incl. tables
Computational Toxicology Summary was prepared by DEREK Nexus version 2.0.2 software, and the result for ocular toxicity is negative.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Derek Nexus software Criteria used for interpretation of results: EU
- Conclusions:
- Computational Toxicology Summary was prepared by DEREK Nexus version 2.0.2 software, and the result for ocular toxicity is negative.
- Executive summary:
Computational Toxicology Summary was prepared by DEREK Nexus version 2.0.2 software, and the result for ocular toxicity is negative.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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