Registration Dossier
Registration Dossier
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EC number: 202-476-7 | CAS number: 96-09-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Data from an OECD guideline study 203 on Carps are available.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 6.9 mg/L
Additional information
Freshwater fish
In a 96-h acute toxicity study performed according to the OECD guideline No. 203, 1992, Carps (Cyprinus carpio, Teleostei, Cyprinidae) were exposed to styrene oxide at nominal concentrations of 4.6, 10, 22, 46 and 100 % (% of the WSF prepared at a loading rate of 100 mg/L) under semi-static conditions. The total test period was 96 hours and samples for analytical confirmation of actual test concentrations were taken at the start and the end of the first and the last refreshment period. Initial concentrations slightly decreased during the renewal periods (67-82 % of initial). Given these results, effect parameters were based on the average exposure concentrations that were calculated to be 1.9, 4.7, 10, 22 and 52 mg/L.
The 96-h LC50 was 6.9 mg/L based on average exposure concentrations (95 % confidence interval between 4.7 and 10 mg/L) and was already reached after 72 hours of exposure.
The NOEC value, based on mortality effects, was 4.7 mg/L. At the end of the test all fish exposed to the three highest test concentrations had died, while all fish exposed to the two lowest concentrations survived without showing any clinical effects.
Marine water fish
No data available.
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