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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
The information does not come from a test report, and only minimum fields required can be filled in.

Data source

Referenceopen allclose all

Reference Type:
other: database
Title:
Triethyl citrate, CAS# 77-93-0, RTECS# GE8050000
Author:
Canadian Centre for Occupational Health & Safety (CCOHS)
Year:
2010
Bibliographic source:
Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963- 81,p. 389; cited in RTECS database (Registry of Toxic Effects of Chemical Substances, 2010)
Reference Type:
other: database
Title:
GESTIS Substance Database: Triethylcitrat
Author:
Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA, Institute for Occupational Safety and Health of the German Social Accident Insurance)
Year:
2010
Bibliographic source:
www.dguv.de/ifa/gestis-database

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Handbook data
GLP compliance:
not specified
Remarks:
Handbook data, with no information on GLP status
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Triethyl citrate
EC Number:
201-070-7
EC Name:
Triethyl citrate
Cas Number:
77-93-0
Molecular formula:
C12H20O7
IUPAC Name:
triethyl citrate

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: other: EU-GHS
Conclusions:
LD50 (rabbit) >5000 mg/kg
Executive summary:

In the Registry of Toxic Effects of Chemical Substances (RTECS) database and the GESTIS substance database a LD50 (rabbit) of 5000 mg/kg bw is reported for triethyl citrate. No further details are available.