Di-tert-butyl peroxide

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 October 2009 – 27 October 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Well conducted study, according to OECD guideline, report including certificate of analysis.

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

July 27th, 1995

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Water solubility:

171 mg/L

Temp.:

20 °C

pH:

8.1

Three sets of samples (in duplicate) were analyzed 24, 48 and 72 hours after weighing of the test substance Trigonox B and addition of water. The concentration of the test substance was quantified using Head-space GC Chromatography. Table 6.1 presents a summary of the three sets of tests performed. The amount of test substance weighed at the start of the test, the pH of the dilutions and the calculated results after analysis are all displayed in Table 1.

 

Table 6.1: Analysis results of Trigonox B water solubility

 

Test time (hours after weighing)		Amount of test substance in water (mg/L)		Intake water (g)		pH		Trigonox B concentration (mg/kg)		average (mg/kg)
24		859 – 813		10.67 – 9.96		8.3		170 – 169		170
48		949 – 842		10.09 – 9.89		8.0		179 – 170		175
72		1232 - 1021		10.11 – 10.11		8.1		167 – 171		169

 

Table 6.2: Summary of the results of Trigonox B water solubility

 

Test time (hours after weighing)		Amount of test substance (mg/L)		pH		Solubility (mg/L)		Difference between solubilities (%)*		Average water solubility (mg/L)
24		approx. 800		8.3		170				171
48		approx. 900		8.0		175		2.9
72		approx. 1000		8.1		169		3.6

 

* According to the guideline the repeatability of two individual results must be less than 15% before averaging.

Conclusions:

Di-tert-butyl peroxide has a water solubility of 171 mg/L at 20°C and pH 8.1.

Executive summary:

The water solubility of di- tert- butyl peroxide was determined according to OECD test guideline 105. The flask method was used to perform the water solubility test because a literature search and a preliminary study indicated that the water solubility would be >100 mg/l. Head- space gas chromatography was used to determine the concentration of the test substance in water. The average water solubility of di- tert- butyl peroxide in this study was determined to be 171 mg/l.

Description of key information

Di-tert-butyl peroxide has a water solubility of 171 mg/L at 20°C and pH 8.1.

Key value for chemical safety assessment

Water solubility:

171 mg/L

at the temperature of:

20 °C

Additional information

This low solubility is supported by calcualted data.