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Registration Dossier
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EC number: 617-892-8 | CAS number: 86604-75-3
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: PhEUR, General Notices
- Deviations:
- no
Test material
- Reference substance name:
- 2-(chloromethyl)-4-methoxy-3,5-dimethylpyridinium chloride
- EC Number:
- 617-892-8
- Cas Number:
- 86604-75-3
- Molecular formula:
- C9H12ClNO.HCl
- IUPAC Name:
- 2-(chloromethyl)-4-methoxy-3,5-dimethylpyridinium chloride
- Details on test material:
- - Name of test material (as cited in study report): Omeprazole chloromethylpyridine
- Substance type: organic
- Physical state: solid
- Analytical purity: 100 % (HPLC area percent)
- Purity test date: 02. 2008
- Lot/batch No.: 30000859
- Expiration date of the lot/batch: 01. 2009
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubilityopen allclose all
- Medium:
- ethanol
- Solubility:
- > 100 - < 1 000 g/L
- Temp.:
- 22 °C
- Medium:
- methanol
- Solubility:
- > 100 - < 1 000 g/L
- Temp.:
- 22 °C
- Test substance stable:
- not determined
- Details on results:
- Freely soluble mean solubility greater between 100 and 1000 g/l according to Pharmacopeia, General Notices.
Any other information on results incl. tables
The result in the COA is written according to the Pharmacopeia and is equal to the numeric result written in this section.
Applicant's summary and conclusion
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