Registration Dossier
Registration Dossier
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EC number: 201-280-9 | CAS number: 80-46-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Davoren and Fogarty (2005) conducted a reliable study with algae where the 72 hr EC50 of 4.2 mg/L and72 hr NOEC of 1.8 mg/L, based on growth, was provided.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 4.2 mg/L
- EC10 or NOEC for freshwater algae:
- 1.8 mg/L
Additional information
A reliable (Klimisch 1 or 2) short-term toxicity study with algae has been conducted for p-tert-amylphenol and is included in this dossier.
Davoren and Fogarty (2005) conducted a reliable (Klimisch 2) study according to American Public Health Association procedure (APHA, 1995) with sodium p-tert-amylphenol with Pseudokirchneriella subcapitata. Data obtained from tests using the salt is assumed to be representative of the parent substance due to its weak acid properties. Algae were exposed to nominal concentrations (1.0-10 mg/L) of the test substance for 96 hours. The 72-hr and 96-hr EC50s, based on growth, are 4.2 and 4.2 mg/L, respectively. The 96-hr EC10 and NOEC, based on growth, are 2.1 and 3.2 mg/L The 72-hr EC10 and NOEC, based on growth, are 0.9 and 1.8 mg/L, respectively.
Adequate reliable measured data exists for toxicity to algae to p-tert-amylphenol. The data point of highest concern for this endpoint has been identified in a reliable study which reports a measured 72 hr EC50 of 4.2 mg/L and 72 hr NOEC of 1.8 mg/L, based on growth, for toxicity to aquatic algae. Consequently these values will be taken as the toxicity in aquatic algae endpoint for p-tert-amylphenol.
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