Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
adverse effect observed
Effect on fertility: via inhalation route
Endpoint conclusion:
no adverse effect observed
Effect on fertility: via dermal route
Endpoint conclusion:
no adverse effect observed
Additional information

Substance specific information for the UVCB substance "Matte, precious metal" is not available for the endpoint "Toxicity to Reproduction" with respect to effects on fertility. In order to meet the requirements for Annex VII till Annex X of Regulation (EC) 1907/2006, read across information from any constituents being relevant needs to be included. Due to the high number of constituents and variability in C&L it was decided to use the classification information from the individual constituents and to calculate the resulting classification by using the Generic concentration limits of ingredients of a mixture classified as reproduction toxicants or for effects on or via lactation that trigger classification of the mixture" and respective rules of Regulation (EC) 1272/2006 section 3.7.3.1 “Classification of mixtures when data are available for all ingredients or only for some ingredients of the mixture” with the MeClas tool.This approach has been presented and discussed with ECHA in several meetings.

In total, tree different grades of "Matte, precious metal" (Matte, precious metal 1 – Matte, precious metal 3) were identified by the consortium that could be grouped according to their calculated C&L resulting from the specific composition profile. Thus, for "Matte, precious metal" one C&L entry (i.e., classification for Repr. 1A) for reproductive toxicity were calculated.


Short description of key information:
No information on animal testing of "Matte, precious metal" is available. However, "Matte, precious metal" contains lead and lead compounds ≥ 0.3 % that may possess reproduction toxicity (i.e., suspected of damaging fertility). Hence, "Matte, precious metal" requires classification as reproductive toxicant.

Effects on developmental toxicity

Description of key information
No information on animal testing of "Matte, precious metal" is available. However, "Matte, precious metal" contains lead and lead compounds ≥ 0.3 % that may possess reproduction toxicity (i.e., may damage the unborn child). Hence, "Matte, precious metal" requires classification as reproductive toxicant.
Effect on developmental toxicity: via oral route
Endpoint conclusion:
adverse effect observed
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no adverse effect observed
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no adverse effect observed
Additional information

Substance specific information for the UVCB substance "Matte, precious metal" is not available for the endpoint "Toxicity to Reproduction" with respect to effects on developmental toxicity. In order to meet the requirements for Annex VII till Annex X of Regulation (EC) 1907/2006, read across information from any constituents being relevant needs to be included. Due to the high number of constituents and variability in C&L it was decided to use the classification information from the individual constituents and to calculate the resulting classification by using the Generic concentration limits of ingredients of a mixture classified as reproduction toxicants or for effects on or via lactation that trigger classification of the mixture" and respective rules of Regulation (EC) 1272/2006 section 3.7.3.1 “Classification of mixtures when data are available for all ingredients or only for some ingredients of the mixture” with the MeClas tool. This approach has been presented and discussed with ECHA in several meetings.

In total, tree different grades of "Matte, precious metal" (Matte, precious metal 1 – Matte, precious metal 3) were identified by the consortium that could be grouped according to their calculated C&L resulting from the specific composition profile.Thus, for "Matte, precious metal" one C&L entry (i.e., classification for Repr. 1A) for reproductive toxicity were calculated.

Justification for classification or non-classification

Reproductive toxicity classification of UVCB substances is based on the presence of a constituent ≥ 0.3 % classified for reproductive toxicity. "Matte, precious metal" contains lead and lead compounds ≥ 0.3 %. Hence, "Matte, precious metal" is considered to induce reproductive toxicity, and requires classification as Repr. 1A (H360Df: may damage the unborn child, suspected of damaging fertility) in accordance with Regulation (EC) 1272/2008.There is not any evidence of effects on or via lactation for any constituents of Matte, precious metalat a concentration≥ 0.3%.

Additional information