Slimes and Sludges, battery scrap, antimony- and lead-rich

Repeated dose toxicity: oral

Administrative data

Endpoint:

repeated dose toxicity: oral

Remarks:

other: calculation

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: automatic calculation tool in development at Eurometaux

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other: software

Title:

Unnamed

Year:

2010

Materials and methods

Principles of method if other than guideline:

The UVCB substance as complex substance is classified regarding STOT-RE by applying rules for classification of mixtures (generic concentration limits EU CLP Guidance Annex I: Table 3.9.4). The classification criteria (as set out in EU CLP Guidance Annex I: 3.9.3) can be used to estimate effects derived from that classification/hazard.

GLP compliance:

no

Remarks:

equivalent quality assurance

Test material

Test material information

Constituent 1

Reference substance name:

Slimes and Sludges, battery scrap, antimony- and lead-rich

EC Number:

310-061-8

EC Name:

Slimes and Sludges, battery scrap, antimony- and lead-rich

Cas Number:

102110-60-1

Molecular formula:

Molecular weigth/formula concept not applicable to Inorganic UVCB (comlex metal containing substance)

IUPAC Name:

Slimes and Sludges, battery scrap, antimony- and lead-rich

Details on test material:

Elemental composition of maximum of typicals across industry: IUCLID Section 1.2
Representative sample(s) for mineralogical information: IUCLID Section 4.23

Results and discussion

Target system / organ toxicity

Critical effects observed:

not specified

Any other information on results incl. tables

The derived classification result (via mixture toxicity rules) for Grade 1 and Grade 2 of Slimes and sludges battery scrap Sb, Pb rich is "Specific target organ toxicity-repeated exposure Category 2; H373" due to the presence of > = 0.5% lead compounds (maximum of typical used to derive the classification: 75.2% lead which is equal to ca. 66% lead compounds since 87.73% of lead is present in the compounds form and 12.27% in metal (powder) form (according to reference sample OR25, see section 4.23)).

Applicant's summary and conclusion

Conclusions:

Study can be used to establish the STOT RE effect of the UVCB substance. The derived classification result (via mixture toxicity rules) for Grade 1 and Grade 2 of Slimes and sludges battery scrap Sb, Pb rich is "Specific target organ toxicity-repeated exposure Category 2; H373" due to the presence of > = 0.5% lead compounds (maximum of typical used to derive the classification: 75.2% lead which is equal to ca. 66% lead compounds since 87.73% of lead is present in the compounds form and 12.27% in metal (powder) form (according to reference sample OR25, see section 4.23)).

Executive summary:

The study provided a conservative estimate of the STOT RE hazard, derived on the basis of the classification outcome (Mixture toxicity rules) from a reasonable worst case sample (maximum of typicals for every constituent) across industry for Slimes and Sludges battery scrap Sb, Pb rich Grade 1 and Grade 2 as defined in IUCLID section 1.2 and the mineralogical information from representative samples (IUCLID section 4.23). The classification result for both grades is "STOT RE Category 2; H373"

due to the presence of > = 0.5% lead compounds (maximum of typical used to derive the classification: 75.2% lead which is equal to ca. 66% lead compounds since 87.73% of lead is present in the compounds form and 12.27% in metal (powder) form (according to reference sample OR25, see section 4.23)).