Registration Dossier
Registration Dossier
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EC number: 225-625-8 | CAS number: 4979-32-2
Repeated dose toxicity: inhalation
Administrative data
- Endpoint:
- short-term repeated dose toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: study data do not give sufficient experimental details
Data source
Reference
- Reference Type:
- publication
- Title:
- N, N-dicyclohexyl-2-benzothiazolesulfenamide
- Author:
- Vorobeva, R.S.,
- Year:
- 1 968
- Bibliographic source:
- Toksikol. Nov. Khim. Veshchestv,|Vnedryaemykh Reszin. Shinnuyu Prom. 1968, 89-93, cited in:|Chem. Abstr. 71: 20566h
Materials and methods
- Principles of method if other than guideline:
- other: subacute inhalation study
- GLP compliance:
- no
Test material
- Reference substance name:
- N,N-dicyclohexylbenzothiazole-2-sulphenamide
- EC Number:
- 225-625-8
- EC Name:
- N,N-dicyclohexylbenzothiazole-2-sulphenamide
- Cas Number:
- 4979-32-2
- Molecular formula:
- C19H26N2S2
- IUPAC Name:
- N-(1,3-benzothiazol-2-ylsulfanyl)-N-cyclohexylcyclohexanamine
- Details on test material:
- no data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male
Administration / exposure
- Route of administration:
- inhalation
- Duration of treatment / exposure:
- 15 d
- Frequency of treatment:
- 2h/d
Doses / concentrations
- Remarks:
- Doses / Concentrations:
340-400 mg/m3
Basis:
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
- Details on study design:
- Post-exposure period: no data
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
No effect except mucous membrane irritation were observed. No pronounced liver or kidney changes were observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
