Registration Dossier
Registration Dossier
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EC number: 201-234-8 | CAS number: 79-92-5
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation, other
- Remarks:
- QSAR prediction
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Internationally accepted QSAR method (Multicase). Prediction by Danish EPA (included in the OECD Toolbox Application).
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR prediction
- Title:
- Unnamed
- Year:
- 1 998
Materials and methods
- Principles of method if other than guideline:
- QSAR prediction by Danish EPA: Multicase model A33 (QPRF document is attached).
Multicase model A33: consists of chemicals reported to be able to induce acute dermatitis in humans and/or guinea pigs. The system includes more than 30 QSARs covering from 3 to 150 molecules with average r2 approximately of 0.8. The expert system yields a predictivity of 84% (Rosenkranz et al. 1999).
Test material
- Reference substance name:
- Camphene
- EC Number:
- 201-234-8
- EC Name:
- Camphene
- Cas Number:
- 79-92-5
- Molecular formula:
- C10H16
- IUPAC Name:
- 2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane
Constituent 1
Results and discussion
Any other information on results incl. tables
The conclusion of the QSAR prediction is that the substance Camphene is not sensitising.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
- Conclusions:
- The conclusion of the QSAR prediction is that the substance Camphene is not sensitising.
- Executive summary:
QSAR prediction by Danish EPA: Multicase model A33.
Multicase model A33: consists of chemicals reported to be able to induce acute dermatitis in humans and/or guinea pigs. The system includes more than 30 QSARs covering from 3 to 150 molecules with average r2 approximately of 0.8. The expert system yields a predictivity of 84% (Rosenkranz et al. 1999).
The conclusion of the QSAR prediction is that the substance Camphene is not sensitising.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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