Registration Dossier
Registration Dossier
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EC number: 203-489-0 | CAS number: 107-41-5
Toxicity to other aquatic organisms
Administrative data
Link to relevant study record(s)
Description of key information
In a non-guideline study conducted prior to ecotoxicity GLP requirements, the LC50 of hexylene glycol to tadpoles (Rana catesbeiana) was reported to be 11800 mg/L.
Additional information
The toxicity of hexylene glycol in tadpoles (Rana catesbeiana) was assessed in a published non-guideline study that predates GLP requirements for ecotoxicity studies (Thurston et al., 1982). Significant methodological deficiencies were identified in this study including lack of reporting of the concentrations that were tested and of the number of animals that were assessed. The tadpoles were exposed to hexylene glycol for 96 hours in a flow-through freshwater exposure system. The 96-hour LC50was reported to be 11800 mg/L (Thurston et al., 1982).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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