2-ethylhexyl salicylate

Endpoint summary

Description of key information

Lowest EC10 (reproduction, daphnia magna): 0.0084 mg/L

Additional information

Valid acute toxicity tests with the test substance are available for three freshwater species from three trophic levels. In all tests the EC/LC50 was higher than the water solubility of the substance (< 0.5 mg/L).

In the algae study no effects were observed in the tested undiluted filtrate with a loading rate of 100 mg/L (NOEC >= 0.011 mg/L). In the Daphnia study 5% immobilization was observed within the limits of water solubility (EC50 > water solubility). In all three fish tests no mortality was observed within water solubility. The key study (Scheerbaum, 1996) showed that even in an emulsion with 100 mg/L nominal, no effects were observed (LC50 > 82 mg/L measured conc.). A study using an emulsifier (Caspers, 1996) showed as well no mortality up to the water solubility limit (LC0 >= 0.22 mg/L; loading rate 2.5 mg/L). In a third study (Caspers, 1992) the toxicity was tested far above the water solubility of the substance (62 to 1000 mg/L). Up to 250 mg/L (nominal) no mortality was observed. The LC50 was determined to be 613 mg/L (nominal), where the mortality can be attributed to physical effects instead of systemic effects.

 

Additionally to the algae test, one further long-term tests with aquatic invertebrates is available. In the flow-through test the EC10 (reproduction) was determined to be 0.0084 mg/L based on mean measured test item concentrations. 

The evaluation of the long-term toxicity on fish is still ongoing (see BoA case number A-010-2018 with a deadline of  25 February 2024).

 

Furthermore a valid respiratory inhibition study with activated sludge is available: The substance did not inhibit the microbial activity in activated sludge up to a nominal concentration of 1000 mg/L. At 10000 mg/L 14.3% inhibition were observed. The EC50 is > 10000 mg/L and the substance is not considered to be toxic to sewage sludge bacteria.