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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

OECD Guideline 209, EU Method C11, EPA OPPTS 850.6800, GLP, key study, validity 1:
3h-EC10 = 89.6 mg/L (95%CL: 57.63 - 139.27 mg/L)
3h-EC50 > 1000 mg/L

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
89.6 mg/L

Additional information

One valid key study is available to assess the toxicity of TBEP to microorganisms. In this 3-h acute toxicity test, activated domestic sewage sludge was exposed to TBEP at nominal concentrations of 0, 10, 31, 100, 313 and 1000 mg/L (nominal concentration). 3, 5-dichlorophenol was used as reference material (positive control) at 5, 16 and 32 mg/L (nominal concentration). The study was performed according to the OECD Guideline No 209 (1984). Maximum respiration inhibition rate was observed at 1000 mg/L of substance. Thus, the 3h-EC50 value was found to be higher than 1000 mg/L. The 3h-EC10 value was calculated to be 89.6 mg/L (95%CL: 57.63 - 139.27 mg/L).