Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Principles of method if other than guideline:
About 5 mL of the test item were filled in a test tube and cooled down using acetone and dry ice until solidification occurred. The probe of a thermocouple was placed in the centre of the sample. The temperature was measured with an appropriate thermocouple. The test was carried out in duplicate. The temperature/time curves were recorded during the cooling of the test item. Additionally, the physical state was observed visually.
GLP compliance:
no
Type of method:
method to determine freezing temperature
Melting / freezing pt.:
-56.5 °C
Remarks on result:
other: Estimated accuracy +/- 0.5°C

A pretest was done to determine that the value was well below -20°C. The test sample was cooled to -70.5°C using a dry ice and acetone bath. The solid test item was then allowed to warm up to -56.7°C, where it became liquid. The process was repeated with the test item becomming liquid at -56.3°C. The mean of the two measurements was taken as the resulting freezing point.

Supercooling was observed in the experiment.

Conclusions:
The freezing point is determined to be -56.5°C (329.7°K)

Description of key information

-56.5°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-56.5 °C

Additional information

A single GLP study (Kuehne 2010) according to OECD guidelines is available and reports the meting point of trimethyl orthoformate to be -56.5°C.