Registration Dossier
Registration Dossier
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EC number: 204-633-5 | CAS number: 123-51-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Reference Type:
- secondary source
- Title:
- Fragrance raw materials monographs - Isoamly alcohol
- Author:
- Opdyke DLJ
- Year:
- 1 978
- Bibliographic source:
- Food Chem. Tox. 16, S1, 785-788
Materials and methods
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 3-methylbutan-1-ol
- EC Number:
- 204-633-5
- EC Name:
- 3-methylbutan-1-ol
- Cas Number:
- 123-51-3
- Molecular formula:
- C5H12O
- IUPAC Name:
- 3-methylbutan-1-ol
- Details on test material:
- - Name of test material (as cited in study report): Isoamylalcohol
- Sample No.: 76-151
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- no data
- Doses:
- no data
- No. of animals per sex per dose:
- 10 animals
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Clinical signs:
- other: Toxic signs were flaccid in 6, ataxia in 7 and loss of righting reflex in 3 all at 1 hour post dose. Diarrhea in 1
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
