Registration Dossier
Registration Dossier
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EC number: 209-218-2 | CAS number: 561-41-1
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo mammalian germ cell study: cytogenicity / chromosome aberration
- Remarks:
- Type of genotoxicity: chromosome aberration
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 561-41-1
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- Rodent, Dom. Lethal (Rodent Dominant Lethal Test): Multicase model
- GLP compliance:
- no
- Type of assay:
- rodent dominant lethal assay
Test material
- Reference substance name:
- 4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol
- EC Number:
- 209-218-2
- EC Name:
- 4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol
- Cas Number:
- 561-41-1
- Molecular formula:
- C24-H29-N3-O
- IUPAC Name:
- bis[4-(dimethylamino)phenyl][4-(methylamino)phenyl]methanol
- Details on test material:
- - Name of test material : 4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol
- Substance type: Organic
- Molecular formula : C24H29N3O
- Molecular weight : 375.5066
Constituent 1
Test animals
- Species:
- other: Rodent
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: No data
Results and discussion
Test results
- Sex:
- not specified
- Genotoxicity:
- not specified
- Toxicity:
- no effects
- Vehicle controls validity:
- not specified
- Negative controls validity:
- not specified
- Positive controls validity:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): negative
4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol gives negative result in Rodent Dominant Lethal Test - Executive summary:
4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol gives negative result in Rodent Dominant Lethal Test
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